Overview
Population biology phenomena such as the spread of alleles in populations, the coexistence of competing species in an ecological community, the branching patterns in phylogenetic trees, and the dynamics of infectious disease are situated in different biology subdisciplines, e.g. demography, ecology, epidemiology, or evolution. However, these disparate phenomena are modeled using shared mathematical approaches. These approaches draw from diverse areas of mathematics, including stochastic processes, mathematical statistics, combinatorics, and dynamical systems. Across biological disciplines, population biologists share interests in the identification and analysis of equilibria, investigation of mechanistic dynamics, network-based methods and spatial modeling, modeling of stage transitions, biological optimality arguments, and the precise mathematical formulation and exploration of the consequences of verbal models. Some mathematical approaches are unique to population biology phenomena, e.g. the exponential amplification of initially rare beneficial variants such that the law of large numbers never applies poses a profound challenge, one which continues to call for new math in the area of stochastic processes.
This workshop aims to crystallize central ideas common across mathematical modeling and theory in population biology; to disseminate mathematical innovations from one biological subdiscipline to another; to promote mathematical studies at intersections among biological subdisciplines, and to deepen interactions among scientists working on similar problems but separated by disciplinary structures within biology, or between biology and the mathematical sciences. The goals are to build a community of theoretical population biologists that spans biological subdisciplines, invite new entrants to the field, encourage early-career scientists, showcase outstanding research, demonstrate impact in societally relevant problems, and uncover promising new directions where modeling and theory can make a difference in studying new types of biological data obtained at the level of populations.

Schedule
June 02 2025 Monday
8:30 am - 8:55 am
Light Breakfast
8:55 am - 9:00 am
Welcome, Introduction of the Institute & Housekeeping – NITMB Leadership
9:00 am - 9:10 am
Workshop Introduction - Joanna Masel
9:10 am - 9:20 am
Noah Rosenberg - SMTPB information
9:20 am - 9:40 am
Nick Barton - Modelling complex traits
9:40 am - 10:00 am
Dandan Peng - Population Genetics Simulations on Phylogenetic Trees: Investigating the Relationship Between Micro and Macro Evolution
10:00 am - 10:20 am
Jason Bertram - Strong amplification of quantitative genetic variation under a balance between mutation and fluctuating stabilizing selection
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
Junjian (Janis) Liu - Error rates in QST-FST comparisons depend on genetic architecture and estimation procedure
11:10 am - 11:30 am
Walid Mawass - Residual confounding bias due to imperfect population stratification control
11:30 am - 11:50 am
Mariadaria Ianni-Ravn - Understanding the Impacts of Multi-Generational Environment Sharing on Phenotypic Covariance
11:50 am - 1:00 pm
Lunch
1:00 pm - 2:15 pm
Parallel Discussion Sessions
1. Rate-dependent phenomena in ecology and evolution
2. An Introduction to Branching Processes and Generating Functions
3. Causal Inference in Population Biology
4. Which parts of population genetic theory need to be rethought in light of realistically high genome-wide deleterious mutation rates in species like humans?
5. Imagining the next generation of social evolution theory
6. SMTPB: Strategies for advocating for modeling to non-theorists
7. Matrix population models and linkages to population genetics, quantitative models, and evolutionary theory.
8. Theory to Control, Mitigate, and Anticipate Infectious Disease Impact
2:15 pm - 2:45 pm
Coffee Break
2:45 pm - 4:00 pm
Parallel Discussion Sessions
1. Rate-dependent phenomena in ecology and evolution
2. An Introduction to Branching Processes and Generating Functions
3. Causal Inference in Population Biology
4. Which parts of population genetic theory need to be rethought in light of realistically high genome-wide deleterious mutation rates in species like humans?
5. Imagining the next generation of social evolution theory
6. SMTPB: Strategies for advocating for modeling to non-theorists
7. Matrix population models and linkages to population genetics, quantitative models, and evolutionary theory.
8. Theory to Control, Mitigate, and Anticipate Infectious Disease Impact
4:00 pm - 6:00 pm
Poster session and drinks
June 03 2025 Tuesday
8:30 am - 8:55 am
Light Breakfast
8:55 am - 9:00 am
Welcome & Housekeeping
9:00 am - 9:30 am
Anuraag Bukkuri - Williamson Prize talk: Eco-Evolutionary Dynamics as an Engine for Cancer Treatment and Drug Discovery
9:30 am - 9:50 am
Motasem ElGamel - Population dynamics and universal statistics of tumor-inhabiting bacteria
9:50 am - 10:10 am
Nicola Mulberry - Can we build lineage trees from single-cell level gene expression data?
10:10 am - 10:30 am
Murat Tugrul - Noise in Cellular Damage Accumulation: Consequences for Ageing and Population Fitness
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Aaron King - Markov genealogy processes: a new mathematical basis for phylodynamics
11:20 am - 11:40 am
Gili Greenbaum - Ecology and evolution in gene drive modeling
11:40 am - 12:00 pm
Hildegard Uecker - Modeling evolutionary rescue: Concepts and applications to bacterial evolution
12:00 pm - 1:00 pm
Lunch
1:00 pm - 2:15 pm
Parallel Discussion Sessions
1. Mathematics and Bureaucracy
2. SMTPB: Undergraduate teaching on modeling & theory
3. Modeling polygenic inheritance with loci of different effect sizes
4. New opportunities in phylodynamics
5. What is an environment? Phenotypes and fitness mapping across environmental scales in the era of cheap fitness measurements
6. Statistics for diversity measurement across population biology
7. Incorporating ecology and evolution into models
8. Establishment probabilities of beneficial alleles when the branching process assumption fails
2:15 pm - 2:45 pm
Coffee Break
2:45 pm - 4:00 pm
Parallel Discussion Sessions
1. Mathematics and Bureaucracy
2. SMTPB: Undergraduate teaching on modeling & theory
3. Modeling polygenic inheritance with loci of different effect sizes
4. New opportunities in phylodynamics
5. What is an environment? Phenotypes and fitness mapping across environmental scales in the era of cheap fitness measurements
6. Statistics for diversity measurement across population biology
7. Incorporating ecology and evolution into models
8. Establishment probabilities of beneficial alleles when the branching process assumption fails
4:15 pm - 6:00 pm
Poster session and drinks
June 04 2025 Wednesday
8:30 am - 8:55 am
Light Breakfast
8:55 am - 9:00 am
Welcome & Housekeeping
9:00 am - 9:20 am
Talia Borofsky - Cooperative hunting and competition for prey shape group formation
9:20 am - 9:40 am
Lilach Hadany - The evolution of cooperation under host-microbiome interactions
9:40 am - 10:00 am
Daniel Priego Espinosa - The effect of background selection on the evolution of altruism in metapopulations
10:00 am - 10:20 am
Farshad Shirani - Evolution of a Species' Range
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:00 am
Sebastian Schreiber - Priority effects in community assembly: Mathematical rigor meets empirical realism
11:10 am - 11:30 am
Zhijie Feng - A linear response theory of ecological invasion
11:30 am - 11:50 am
Fernanda Valdovinos - A bioenergetic framework for aboveground terrestrial food webs
11:50 am - 1:00 pm
Lunch
1:00 pm - 2:15 pm
Parallel Discussion Sessions
1. SMTPB: Online events & future meetings
2. Enhancing Communication and Understanding of Theoretical Models in Population Biology through Dynamic Visualizations
3. Accounting for unequal variance in mixed-ploidy population genetics
4. Modeling the evolution of recombination landscapes
5. Multiplicative noise in ecological dynamics
6. The informativeness of alleles for mixed-membership cluster assignment
7. Adaptation in spatially and temporally varying environments
8. Scale-independent, rank-statistic based definition of epistasis
2:15 pm - 2:45 pm
Coffee Break
2:45 pm - 4:00 pm
Parallel Discussion Sessions
4:00 pm
Excursion
June 05 2025 Thursday
8:30 am - 8:55 am
Light Breakfast
8:55 am - 9:00 am
Welcome & Housekeeping
9:00 am - 9:20 am
John Wakeley - Coalescent processes conditional on the population pedigree when there is selfing
9:20 am - 9:40 am
Diego Veliz-Otani - Genetic Relationship Matrices calculated from whole-genome sequence data can capture evolutionary relationships at all time scales
9:40 am - 10:00 am
Daniel Weissman - The time to the most recent genetic common ancestor
10:00 am - 10:20 am
Hao Shen - Efficient computation of expected pairwise coalescent times in the structured coalescent
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
Lily Tamir - Combinatorics of time-consistent galled trees
11:10 am - 11:30 am
Jaehee Kim - Population genetics of dormancy
11:30 am - 11:50 am
John McEnany - Rapid evolution in a fluctuating environment
11:50 am - 1:00 pm
Lunch
1:00 pm - 2:30 pm
Parallel Discussion Sessions
2:30 pm - 3:00 pm
Coffee Break
3:00 pm - 4:30 pm
Parallel Discussion Sessions
4:30 pm - 6:00 pm
Reception with drinks and appetizers (in-suite)
June 06 2025 Friday
8:30 am - 8:55 am
Light Breakfast
8:55 am - 9:00 am
Welcome & Housekeeping
9:00 am - 9:20 am
Anastasia (Nastia) Lyulina - The site-frequency spectrum under selection and time-varying demography
9:20 am - 9:40 am
Jiawei Liu - MultiSEED: a Theoretical Framework to Predict the Long-term Strain Diversity
9:40 am - 10:00 am
Puneeth Deraje - The Brownian bridge and its extensions: Applications to spatial inference, phylogenetics and population genetics
10:00 am - 10:20 am
Florian Labourel - Beta-binomial distributions and the population genetics view of systems biology
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
Jhelam Nitin Deshpande - Pleiotropic trajectories of evolution when there is global epistasis
11:10 am - 11:30 am
Claire Godineau - How Inbreeding Depression in Growth Shapes Competition and Fitness: Insights from a New Ecological Model
11:30 am - 11:50 am
Bret Payseur - Elevated mutation near crossovers inhibits the evolution of recombination
11:50 am - 12:00 pm
Noah Rosenberg - Talk and poster prize announcements
12:00 pm - 1:00 pm
Lunch
1:00 pm
Stay as long as you like at NITMB
Participants
Participants
Karen Abbott
Daniel Abrams
Frederick Adler
Kennedy Agwamba
Erol Akcay
Stefano Allesina
Kieran Althaus
Daniel Barrow
Daniel Bauman
Darar Bega
Jeremy Berg
Jason Bertram
Aalhad Bhatt
George Brooks
Anuraag Bukkuri
Tianyu Cheng
Tianyu Cheng
Aruni Chenxi
Jie Deng
Puneeth Deraje
Jhelam Deshpande Nitin
Bradley Duda
Motasem ElGamel
Daniel Espinosa Priego
Wai Fan
Zhijie Feng
James Ferrare
Adam Fine
Cody Fitzgerald
Jennifer Foot
Olivia Ghosh
Deepjyoti Ghosh
Claire Godineau
Amy Goldberg
Benjamin Good
Brandon Grandison
Gil Greenbaum
Lilach Hadany
Cristian Huepe
Mariadaria Ianni-Ravn
Kavita Jain
Aaron King
Katharina Koelle
Amber Lee
Junjian Liu
Jiawei Liu
Anastasia Lyulina
Micaila Marcelle
Joanna Masel
Walid Mawass
John McEnany
Rohan Mehta
Nicole Mideo
Maike Morrison
Lauren Mossman
Andrew Mugler
Nicola Mulberry
Obadiah Mulder
Pavitra Muralidhar
Shirin Nataneli
John Novembre
Brandon Ogbunugafor
Maria Orive
Feriel Ouerghi
Bret Payseur
Dandan Peng
Erga Peter
Jitka Polechova
Sohini Ramachandran
Noah Rosenberg
Sebastian Schreiber
Sumit Sen
Athmanathan Senthilnathan
Maria Servedio
Sofia Sheikh
Sofia Sheikh
Chloe Shiff
Farshad Shirani
Margaret Simon
Daniel Smith
Yogev Spilman
Natanael Spisak
Matthias Steinruecken
Alaina Stockdill
Avinash Subramanian
Avinash Subramanian
N Weragoda Surasinghe Vidanelage Sudam
Lily Tamir
Murat Tugrul
Hildegard Uecker
Fernanda Valdovinos
Diego Veliz-Otani
Linda Wahl
John Wakeley
Daniel Weissman
Jonathan Wiese
Katerina Winkler
Peiyu Xu
Mete Yuksel
Yiwen Zhou
Ulises del Campo Hernandez Martin
Jeremy van Cleve
Recordings
Nick Barton
Recorded on 6/2/2025
Title: Modelling complex traits
Claire Godineau
Recorded on 6/2/2025
Title: How Inbreeding Depression in Growth Shapes Competition and Fitness: Insights from a New Ecological Model
Jason Bertram
Recorded on 6/2/2025
Title: Strong amplification of quantitative genetic variation under a balance between mutation and fluctuating stabilizing selection
Junjian (Janis) Liu
Recorded on 6/2/2025
Title: Error rates in QST-FST comparisons depend on genetic architecture and estimation procedure
Walid Mawass
Recorded on 6/2/2025
Title: Residual confounding bias due to imperfect population stratification control
Mariadaria Ianni-Ravn
Recorded on 6/2/2025
Title: Understanding the Impacts of Multi-Generational Environment Sharing on Phenotypic Covariance
Anuraag Bukkuri
Recorded on 6/3/2025
Title: Williamson Prize talk: Eco-Evolutionary Dynamics as an Engine for Cancer Treatment and Drug Discovery
Motasem ElGamel
Recorded on 6/3/2025
Title: Population dynamics and universal statistics of tumor-inhabiting bacteria
Nicola Mulberry
Recorded on 6/3/2025
Title: Can we build lineage trees from single-cell level gene expression data?
Murat Tugrul
Recorded on 6/3/2025
Title: Noise in Cellular Damage Accumulation: Consequences for Ageing and Population Fitness
Aaron King
Recorded on 6/3/2025
Title: Markov genealogy processes: a new mathematical basis for phylodynamics
Gili Greenbaum
Recorded on 6/3/2025
Title: Ecology and evolution in gene drive modeling
Hildegard Uecker
Recorded on 6/3/2025
Title: Modeling evolutionary rescue: Concepts and applications to bacterial evolution
Talia Borofsky
Recorded on 6/4/2025
Title: Cooperative hunting and competition for prey shape group formation
Lilach Hadany
Recorded on 6/4/2025
Title: The evolution of cooperation under host-microbiome interactions
Daniel Priego Espinosa
Recorded on 6/4/2025
Title: The effect of background selection on the evolution of altruism in metapopulations
Farshad Shirani
Recorded on 6/4/2025
Title: Evolution of a Species’ Range
Sebastian Schreiber
Recorded on 6/4/2025
Title: Priority effects in community assembly: Mathematical rigor meets empirical realism
Zhijie Feng
Recorded on 6/4/2025
Title: A linear response theory of ecological invasion
Fernanda Valdovinos
Recorded on 6/4/2025
Title: A bioenergetic framework for aboveground terrestrial food webs
John Wakeley
Recorded on 6/5/2025
Title: Coalescent processes conditional on the population pedigree when there is selfing
Diego Veliz-Otani
Recorded on 6/5/2025
Title: Genetic Relationship Matrices calculated from whole-genome sequence data can capture evolutionary relationships at all time scales
Daniel Weissman
Recorded on 6/5/2025
Title: The time to the most recent genetic common ancestor
Hao Shen
Recorded on 6/5/2025
Title: Efficient computation of expected pairwise coalescent times in the structured coalescent
Lily Tamir
Recorded on 6/5/2025
Title: Combinatorics of time-consistent galled trees
Jaehee Kim
Recorded on 6/5/2025
Title: Population genetics of dormancy
John McEnany
Recorded on 6/5/2025
Title: Rapid evolution in a fluctuating environment
Jiawei Liu
Recorded on 6/6/2025
Title: MultiSEED: a Theoretical Framework to Predict the Long-term Strain Diversity
Puneeth Deraje
Recorded on 6/6/2025
Title: The Brownian bridge and its extensions: Applications to spatial inference, phylogenetics and population genetics
Florian Labourel
Recorded on 6/6/2025
Title: Beta-binomial distributions and the population genetics view of systems biology
Jhelam Nitin Deshpande
Recorded on 6/6/2025
Title: Pleiotropic trajectories of evolution when there is global epistasis
Dandan Peng
Recorded on 6/6/2025
Title: Does Polygenic Adaptation Leave a Molecular Trace
Bret Payseur
Recorded on 6/6/2025
Title: Elevated mutation near crossovers inhibits the evolution of recombination